Much like its predecessor, Separation Anxiety places you in control of either Spider-Man or Venom, a criminal vigilante who possesses Spider-Man's powers and even greater strength. Both characters have different strengths and attack moves. Spider-Man is faster and more agile than Venom, and his special “power-moves” include a grab-and-kick move and a tornado kick. Venom is stronger, but slower than Spider-Man. His power-moves include a powerful uppercut and pounding the ground to hurt everyone in the vicinity. Two player can play both characters simultaneously – which means the plot has been devised to justify the superhero working alongside the villain: both of them must co-operate to stop the alien symbiotes from creating an unstoppable army.

The levels are quite bland, with none of the nifty variety of Maximum Carnage (such as the rooftop scenes). The variety of enemies is similarly disappointing: you’ll run into a maximum of only 2-3 enemy types per level. The characters also look blurry and not very well animated – this PC version looks even worse than the Genesis/SNES version.

Overall, Separation Anxiety is worth playing only if you’re a die-hard fan of Spider-Man. I recommend you stay clear of this average underdog and play the vastly superior and much more atmospheric Maximum Carnage on SNES emulator instead.